messages
listlengths 2
2
|
|---|
[
{
"role": "user",
"content": "Does the compound Dextromethorphan associate with the gene CHRNA3?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there relationship between the drug Nefazodone and the gene CHRNA3?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Isoflurophate and CHRNA3?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Degarelix be able to bind CHRNA3?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Might Pentosan Polysulfate bind functionally to the gene product of FGF1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Does current data suggest that Mianserin targets FGF1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is FGF1 a plausible target for the compound Agomelatine?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does current data suggest that Heroin targets FGF1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Marimastat be able to bind MMP8?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is MMP8 a plausible target for the compound Carteolol?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Nitroglycerin potentially interact with the gene MMP8?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does Cyproheptadine exhibit affinity toward the target gene MMP8?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Dezocine interact directly or indirectly with OPRM1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there a link between Eletriptan and OPRM1 indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Rabeprazole and OPRM1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Piperazine and OPRM1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Prazepam and GABRB1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Can the compound Spaglumic Acid potentially interact with the gene GABRB1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Moclobemide and GABRB1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Acetylcysteine potentially interact with the gene GABRB1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there any known binding between Pravastatin and CYP3A5?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Does the compound Didanosine associate with the gene CYP3A5?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does Azilsartan medoxomil exhibit affinity toward the target gene CYP3A5?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Sibutramine and CYP3A5 indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Might Fentanyl bind functionally to the gene product of CYP3A7-CYP3A51P?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Can the compound Calcitriol potentially interact with the gene CYP3A7-CYP3A51P?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Telaprevir potentially interact with the gene CYP3A7-CYP3A51P?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Agomelatine interact directly or indirectly with CYP3A7-CYP3A51P?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Dorzolamide interact directly or indirectly with CA6?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there a link between Dutasteride and CA6 indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that Doxapram binds to or modulates CA6?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Topiramate and CA6?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Might L-Proline bind functionally to the gene product of PROSC?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Could Gabapentin interact directly or indirectly with PROSC?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Valproic Acid and PROSC indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Cefoperazone potentially interact with the gene PROSC?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Olsalazine and ALOX5 indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Might Methylscopolamine bromide bind functionally to the gene product of ALOX5?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does current data suggest that Tipranavir targets ALOX5?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that Cefotiam binds to or modulates ALOX5?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Valproic Acid be able to bind PTGS1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Would Fluocinonide be able to bind PTGS1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there any known binding between Thiopental and PTGS1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Spectinomycin and PTGS1 indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there relationship between the drug Bethanidine and the gene KCNJ1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is KCNJ1 a plausible target for the compound Etonogestrel?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does Tymazoline exhibit affinity toward the target gene KCNJ1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Dexbrompheniramine interact directly or indirectly with KCNJ1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Droxidopa and SLC6A2?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Chenodeoxycholic acid and SLC6A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that Ergotamine binds to or modulates SLC6A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Theophylline potentially interact with the gene SLC6A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Nifedipine and CACNA1H?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there a link between Fosphenytoin and CACNA1H indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Latanoprost and CACNA1H indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that Warfarin binds to or modulates CACNA1H?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Pantoprazole interact directly or indirectly with CYP1A2?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there any known binding between Nizatidine and CYP1A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does the compound Hexobarbital associate with the gene CYP1A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Fludarabine and CYP1A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Sildenafil be able to bind CYP3A4?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Does current data suggest that Nedocromil targets CYP3A4?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there any known binding between Acetylcysteine and CYP3A4?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Nepafenac potentially interact with the gene CYP3A4?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that L-Tryptophan binds to or modulates WARS2?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Does the compound Indapamide associate with the gene WARS2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Timolol and WARS2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Cerulenin be able to bind WARS2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is SCN3A a plausible target for the compound Zonisamide?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is SCN3A a plausible target for the compound Allopurinol?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does Lercanidipine exhibit affinity toward the target gene SCN3A?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Dipyridamole interact directly or indirectly with SCN3A?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Cysteamine and NPY2R?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Metoprolol and NPY2R?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Darifenacin interact directly or indirectly with NPY2R?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Might Amphetamine bind functionally to the gene product of NPY2R?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Levothyroxine interact directly or indirectly with SLCO4C1?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Might Aspartame bind functionally to the gene product of SLCO4C1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there relationship between the drug Sildenafil and the gene SLCO4C1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can we infer a potential binding event between Flupirtine and SLCO4C1?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Clonidine be able to bind ADRA1A?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is ADRA1A a plausible target for the compound Bethanechol?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Adenosine interact directly or indirectly with ADRA1A?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would L-Leucine be able to bind ADRA1A?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Halofantrine and CYP2C8?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is there relationship between the drug Aminophenazone and the gene CYP2C8?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Metocurine be able to bind CYP2C8?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is it likely that Sufentanil binds to or modulates CYP2C8?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could there be a biochemical interaction between Fospropofol and ALB?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Could Oxybutynin interact directly or indirectly with ALB?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there a link between Enzalutamide and ALB indicating a possible binding relationship?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Teniposide interact directly or indirectly with ALB?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Ephedrine potentially interact with the gene SLC18A2?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Can the compound Histamine Phosphate potentially interact with the gene SLC18A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Does Hydroxystilbamidine Isethionate exhibit affinity toward the target gene SLC18A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Could Cefapirin interact directly or indirectly with SLC18A2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Would Clotiazepam be able to bind GABRB2?"
},
{
"role": "assistant",
"content": "Yes"
}
] |
[
{
"role": "user",
"content": "Is GABRB2 a plausible target for the compound Deferiprone?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Can the compound Isothipendyl potentially interact with the gene GABRB2?"
},
{
"role": "assistant",
"content": "No"
}
] |
[
{
"role": "user",
"content": "Is there relationship between the drug Desflurane and the gene GABRB2?"
},
{
"role": "assistant",
"content": "No"
}
] |
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