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Dec 11

R2MED: A Benchmark for Reasoning-Driven Medical Retrieval

Current medical retrieval benchmarks primarily emphasize lexical or shallow semantic similarity, overlooking the reasoning-intensive demands that are central to clinical decision-making. In practice, physicians often retrieve authoritative medical evidence to support diagnostic hypotheses. Such evidence typically aligns with an inferred diagnosis rather than the surface form of a patient's symptoms, leading to low lexical or semantic overlap between queries and relevant documents. To address this gap, we introduce R2MED, the first benchmark explicitly designed for reasoning-driven medical retrieval. It comprises 876 queries spanning three tasks: Q&A reference retrieval, clinical evidence retrieval, and clinical case retrieval. These tasks are drawn from five representative medical scenarios and twelve body systems, capturing the complexity and diversity of real-world medical information needs. We evaluate 15 widely-used retrieval systems on R2MED and find that even the best model achieves only 31.4 nDCG@10, demonstrating the benchmark's difficulty. Classical re-ranking and generation-augmented retrieval methods offer only modest improvements. Although large reasoning models improve performance via intermediate inference generation, the best results still peak at 41.4 nDCG@10. These findings underscore a substantial gap between current retrieval techniques and the reasoning demands of real clinical tasks. We release R2MED as a challenging benchmark to foster the development of next-generation medical retrieval systems with enhanced reasoning capabilities. Data and code are available at https://github.com/R2MED/R2MED

  • 3 authors
·
May 20

POLYRAG: Integrating Polyviews into Retrieval-Augmented Generation for Medical Applications

Large language models (LLMs) have become a disruptive force in the industry, introducing unprecedented capabilities in natural language processing, logical reasoning and so on. However, the challenges of knowledge updates and hallucination issues have limited the application of LLMs in medical scenarios, where retrieval-augmented generation (RAG) can offer significant assistance. Nevertheless, existing retrieve-then-read approaches generally digest the retrieved documents, without considering the timeliness, authoritativeness and commonality of retrieval. We argue that these approaches can be suboptimal, especially in real-world applications where information from different sources might conflict with each other and even information from the same source in different time scale might be different, and totally relying on this would deteriorate the performance of RAG approaches. We propose PolyRAG that carefully incorporate judges from different perspectives and finally integrate the polyviews for retrieval augmented generation in medical applications. Due to the scarcity of real-world benchmarks for evaluation, to bridge the gap we propose PolyEVAL, a benchmark consists of queries and documents collected from real-world medical scenarios (including medical policy, hospital & doctor inquiry and healthcare) with multiple tagging (e.g., timeliness, authoritativeness) on them. Extensive experiments and analysis on PolyEVAL have demonstrated the superiority of PolyRAG.

  • 8 authors
·
Apr 21

Medical Graph RAG: Towards Safe Medical Large Language Model via Graph Retrieval-Augmented Generation

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called MedGraphRAG, aimed at enhancing Large Language Model (LLM) capabilities and generating evidence-based results, thereby improving safety and reliability when handling private medical data. Our comprehensive pipeline begins with a hybrid static-semantic approach to document chunking, significantly improving context capture over traditional methods. Extracted entities are used to create a three-tier hierarchical graph structure, linking entities to foundational medical knowledge sourced from medical papers and dictionaries. These entities are then interconnected to form meta-graphs, which are merged based on semantic similarities to develop a comprehensive global graph. This structure supports precise information retrieval and response generation. The retrieval process employs a U-retrieve method to balance global awareness and indexing efficiency of the LLM. Our approach is validated through a comprehensive ablation study comparing various methods for document chunking, graph construction, and information retrieval. The results not only demonstrate that our hierarchical graph construction method consistently outperforms state-of-the-art models on multiple medical Q\&A benchmarks, but also confirms that the responses generated include source documentation, significantly enhancing the reliability of medical LLMs in practical applications. Code will be at: https://github.com/MedicineToken/Medical-Graph-RAG/tree/main

  • 3 authors
·
Aug 7, 2024

MedExpQA: Multilingual Benchmarking of Large Language Models for Medical Question Answering

Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances in Medical QA. However, while impressive, the required quality bar for medical applications remains far from being achieved. Currently, LLMs remain challenged by outdated knowledge and by their tendency to generate hallucinated content. Furthermore, most benchmarks to assess medical knowledge lack reference gold explanations which means that it is not possible to evaluate the reasoning of LLMs predictions. Finally, the situation is particularly grim if we consider benchmarking LLMs for languages other than English which remains, as far as we know, a totally neglected topic. In order to address these shortcomings, in this paper we present MedExpQA, the first multilingual benchmark based on medical exams to evaluate LLMs in Medical Question Answering. To the best of our knowledge, MedExpQA includes for the first time reference gold explanations written by medical doctors which can be leveraged to establish various gold-based upper-bounds for comparison with LLMs performance. Comprehensive multilingual experimentation using both the gold reference explanations and Retrieval Augmented Generation (RAG) approaches show that performance of LLMs still has large room for improvement, especially for languages other than English. Furthermore, and despite using state-of-the-art RAG methods, our results also demonstrate the difficulty of obtaining and integrating readily available medical knowledge that may positively impact results on downstream evaluations for Medical Question Answering. So far the benchmark is available in four languages, but we hope that this work may encourage further development to other languages.

  • 3 authors
·
Apr 8, 2024

Multi-OphthaLingua: A Multilingual Benchmark for Assessing and Debiasing LLM Ophthalmological QA in LMICs

Current ophthalmology clinical workflows are plagued by over-referrals, long waits, and complex and heterogeneous medical records. Large language models (LLMs) present a promising solution to automate various procedures such as triaging, preliminary tests like visual acuity assessment, and report summaries. However, LLMs have demonstrated significantly varied performance across different languages in natural language question-answering tasks, potentially exacerbating healthcare disparities in Low and Middle-Income Countries (LMICs). This study introduces the first multilingual ophthalmological question-answering benchmark with manually curated questions parallel across languages, allowing for direct cross-lingual comparisons. Our evaluation of 6 popular LLMs across 7 different languages reveals substantial bias across different languages, highlighting risks for clinical deployment of LLMs in LMICs. Existing debiasing methods such as Translation Chain-of-Thought or Retrieval-augmented generation (RAG) by themselves fall short of closing this performance gap, often failing to improve performance across all languages and lacking specificity for the medical domain. To address this issue, We propose CLARA (Cross-Lingual Reflective Agentic system), a novel inference time de-biasing method leveraging retrieval augmented generation and self-verification. Our approach not only improves performance across all languages but also significantly reduces the multilingual bias gap, facilitating equitable LLM application across the globe.

  • 17 authors
·
Dec 18, 2024

HierSearch: A Hierarchical Enterprise Deep Search Framework Integrating Local and Web Searches

Recently, large reasoning models have demonstrated strong mathematical and coding abilities, and deep search leverages their reasoning capabilities in challenging information retrieval tasks. Existing deep search works are generally limited to a single knowledge source, either local or the Web. However, enterprises often require private deep search systems that can leverage search tools over both local and the Web corpus. Simply training an agent equipped with multiple search tools using flat reinforcement learning (RL) is a straightforward idea, but it has problems such as low training data efficiency and poor mastery of complex tools. To address the above issue, we propose a hierarchical agentic deep search framework, HierSearch, trained with hierarchical RL. At the low level, a local deep search agent and a Web deep search agent are trained to retrieve evidence from their corresponding domains. At the high level, a planner agent coordinates low-level agents and provides the final answer. Moreover, to prevent direct answer copying and error propagation, we design a knowledge refiner that filters out hallucinations and irrelevant evidence returned by low-level agents. Experiments show that HierSearch achieves better performance compared to flat RL, and outperforms various deep search and multi-source retrieval-augmented generation baselines in six benchmarks across general, finance, and medical domains.

  • 7 authors
·
Aug 11 3

Optimizing Retrieval-Augmented Generation: Analysis of Hyperparameter Impact on Performance and Efficiency

Large language models achieve high task performance yet often hallucinate or rely on outdated knowledge. Retrieval-augmented generation (RAG) addresses these gaps by coupling generation with external search. We analyse how hyperparameters influence speed and quality in RAG systems, covering Chroma and Faiss vector stores, chunking policies, cross-encoder re-ranking, and temperature, and we evaluate six metrics: faithfulness, answer correctness, answer relevancy, context precision, context recall, and answer similarity. Chroma processes queries 13% faster, whereas Faiss yields higher retrieval precision, revealing a clear speed-accuracy trade-off. Naive fixed-length chunking with small windows and minimal overlap outperforms semantic segmentation while remaining the quickest option. Re-ranking provides modest gains in retrieval quality yet increases runtime by roughly a factor of 5, so its usefulness depends on latency constraints. These results help practitioners balance computational cost and accuracy when tuning RAG systems for transparent, up-to-date responses. Finally, we re-evaluate the top configurations with a corrective RAG workflow and show that their advantages persist when the model can iteratively request additional evidence. We obtain a near-perfect context precision (99%), which demonstrates that RAG systems can achieve extremely high retrieval accuracy with the right combination of hyperparameters, with significant implications for applications where retrieval quality directly impacts downstream task performance, such as clinical decision support in healthcare.

  • 4 authors
·
May 13 2

RULE: Reliable Multimodal RAG for Factuality in Medical Vision Language Models

The recent emergence of Medical Large Vision Language Models (Med-LVLMs) has enhanced medical diagnosis. However, current Med-LVLMs frequently encounter factual issues, often generating responses that do not align with established medical facts. Retrieval-Augmented Generation (RAG), which utilizes external knowledge, can improve the factual accuracy of these models but introduces two major challenges. First, limited retrieved contexts might not cover all necessary information, while excessive retrieval can introduce irrelevant and inaccurate references, interfering with the model's generation. Second, in cases where the model originally responds correctly, applying RAG can lead to an over-reliance on retrieved contexts, resulting in incorrect answers. To address these issues, we propose RULE, which consists of two components. First, we introduce a provably effective strategy for controlling factuality risk through the calibrated selection of the number of retrieved contexts. Second, based on samples where over-reliance on retrieved contexts led to errors, we curate a preference dataset to fine-tune the model, balancing its dependence on inherent knowledge and retrieved contexts for generation. We demonstrate the effectiveness of RULE on three medical VQA datasets, achieving an average improvement of 20.8% in factual accuracy. We publicly release our benchmark and code in https://github.com/richard-peng-xia/RULE.

  • 8 authors
·
Jul 6, 2024 3

Improving Retrieval-Augmented Generation in Medicine with Iterative Follow-up Questions

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates. While Retrieval-Augmented Generation (RAG) has been proposed to enhance the medical question-answering capabilities of LLMs with external knowledge bases, it may still fail in complex cases where multiple rounds of information-seeking are required. To address such an issue, we propose iterative RAG for medicine (i-MedRAG), where LLMs can iteratively ask follow-up queries based on previous information-seeking attempts. In each iteration of i-MedRAG, the follow-up queries will be answered by a vanilla RAG system and they will be further used to guide the query generation in the next iteration. Our experiments show the improved performance of various LLMs brought by i-MedRAG compared with vanilla RAG on complex questions from clinical vignettes in the United States Medical Licensing Examination (USMLE), as well as various knowledge tests in the Massive Multitask Language Understanding (MMLU) dataset. Notably, our zero-shot i-MedRAG outperforms all existing prompt engineering and fine-tuning methods on GPT-3.5, achieving an accuracy of 69.68\% on the MedQA dataset. In addition, we characterize the scaling properties of i-MedRAG with different iterations of follow-up queries and different numbers of queries per iteration. Our case studies show that i-MedRAG can flexibly ask follow-up queries to form reasoning chains, providing an in-depth analysis of medical questions. To the best of our knowledge, this is the first-of-its-kind study on incorporating follow-up queries into medical RAG.

  • 6 authors
·
Aug 1, 2024

Rethinking Retrieval-Augmented Generation for Medicine: A Large-Scale, Systematic Expert Evaluation and Practical Insights

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented generation (RAG) has been widely adopted to address these limitations by supplementing model outputs with retrieved evidence. However, whether RAG reliably achieves these goals remains unclear. Here, we present the most comprehensive expert evaluation of RAG in medicine to date. Eighteen medical experts contributed a total of 80,502 annotations, assessing 800 model outputs generated by GPT-4o and Llama-3.1-8B across 200 real-world patient and USMLE-style queries. We systematically decomposed the RAG pipeline into three components: (i) evidence retrieval (relevance of retrieved passages), (ii) evidence selection (accuracy of evidence usage), and (iii) response generation (factuality and completeness of outputs). Contrary to expectation, standard RAG often degraded performance: only 22% of top-16 passages were relevant, evidence selection remained weak (precision 41-43%, recall 27-49%), and factuality and completeness dropped by up to 6% and 5%, respectively, compared with non-RAG variants. Retrieval and evidence selection remain key failure points for the model, contributing to the overall performance drop. We further show that simple yet effective strategies, including evidence filtering and query reformulation, substantially mitigate these issues, improving performance on MedMCQA and MedXpertQA by up to 12% and 8.2%, respectively. These findings call for re-examining RAG's role in medicine and highlight the importance of stage-aware evaluation and deliberate system design for reliable medical LLM applications.

  • 27 authors
·
Nov 10

CoFE-RAG: A Comprehensive Full-chain Evaluation Framework for Retrieval-Augmented Generation with Enhanced Data Diversity

Retrieval-Augmented Generation (RAG) aims to enhance large language models (LLMs) to generate more accurate and reliable answers with the help of the retrieved context from external knowledge sources, thereby reducing the incidence of hallucinations. Despite the advancements, evaluating these systems remains a crucial research area due to the following issues: (1) Limited data diversity: The insufficient diversity of knowledge sources and query types constrains the applicability of RAG systems; (2) Obscure problems location: Existing evaluation methods have difficulty in locating the stage of the RAG pipeline where problems occur; (3) Unstable retrieval evaluation: These methods often fail to effectively assess retrieval performance, particularly when the chunking strategy changes. To tackle these challenges, we propose a Comprehensive Full-chain Evaluation (CoFE-RAG) framework to facilitate thorough evaluation across the entire RAG pipeline, including chunking, retrieval, reranking, and generation. To effectively evaluate the first three phases, we introduce multi-granularity keywords, including coarse-grained and fine-grained keywords, to assess the retrieved context instead of relying on the annotation of golden chunks. Moreover, we release a holistic benchmark dataset tailored for diverse data scenarios covering a wide range of document formats and query types. We demonstrate the utility of the CoFE-RAG framework by conducting experiments to evaluate each stage of RAG systems. Our evaluation method provides unique insights into the effectiveness of RAG systems in handling diverse data scenarios, offering a more nuanced understanding of their capabilities and limitations.

  • 5 authors
·
Oct 16, 2024

Tool Calling: Enhancing Medication Consultation via Retrieval-Augmented Large Language Models

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been utilized to provide external knowledge to facilitate the answer generation. However, applying such models to the medical domain faces several challenges due to the lack of domain-specific knowledge and the intricacy of real-world scenarios. In this study, we explore LLMs with RAG framework for knowledge-intensive tasks in the medical field. To evaluate the capabilities of LLMs, we introduce MedicineQA, a multi-round dialogue benchmark that simulates the real-world medication consultation scenario and requires LLMs to answer with retrieved evidence from the medicine database. MedicineQA contains 300 multi-round question-answering pairs, each embedded within a detailed dialogue history, highlighting the challenge posed by this knowledge-intensive task to current LLMs. We further propose a new Distill-Retrieve-Read framework instead of the previous Retrieve-then-Read. Specifically, the distillation and retrieval process utilizes a tool calling mechanism to formulate search queries that emulate the keyword-based inquiries used by search engines. With experimental results, we show that our framework brings notable performance improvements and surpasses the previous counterparts in the evidence retrieval process in terms of evidence retrieval accuracy. This advancement sheds light on applying RAG to the medical domain.

  • 8 authors
·
Apr 27, 2024

Frustratingly Simple Retrieval Improves Challenging, Reasoning-Intensive Benchmarks

Retrieval-augmented Generation (RAG) has primarily been studied in limited settings, such as factoid question answering; more challenging, reasoning-intensive benchmarks have seen limited success from minimal RAG. In this work, we challenge this prevailing view on established, reasoning-intensive benchmarks: MMLU, MMLU Pro, AGI Eval, GPQA, and MATH. We identify a key missing component in prior work: a usable, web-scale datastore aligned with the breadth of pretraining data. To this end, we introduce CompactDS: a diverse, high-quality, web-scale datastore that achieves high retrieval accuracy and subsecond latency on a single-node. The key insights are (1) most web content can be filtered out without sacrificing coverage, and a compact, high-quality subset is sufficient; and (2) combining in-memory approximate nearest neighbor (ANN) retrieval and on-disk exact search balances speed and recall. Using CompactDS, we show that a minimal RAG pipeline achieves consistent accuracy improvements across all benchmarks and model sizes (8B--70B), with relative gains of 10% on MMLU, 33% on MMLU Pro, 14% on GPQA, and 19% on MATH. No single data source suffices alone, highlighting the importance of diversity of sources (web crawls, curated math, academic papers, textbooks). Finally, we show that our carefully designed in-house datastore matches or outperforms web search engines such as Google Search, as well as recently proposed, complex agent-based RAG systems--all while maintaining simplicity, reproducibility, and self-containment. We release CompactDS and our retrieval pipeline, supporting future research exploring retrieval-based AI systems.

  • 5 authors
·
Jul 1

AutoMIR: Effective Zero-Shot Medical Information Retrieval without Relevance Labels

Medical information retrieval (MIR) is essential for retrieving relevant medical knowledge from diverse sources, including electronic health records, scientific literature, and medical databases. However, achieving effective zero-shot dense retrieval in the medical domain poses substantial challenges due to the lack of relevance-labeled data. In this paper, we introduce a novel approach called Self-Learning Hypothetical Document Embeddings (SL-HyDE) to tackle this issue. SL-HyDE leverages large language models (LLMs) as generators to generate hypothetical documents based on a given query. These generated documents encapsulate key medical context, guiding a dense retriever in identifying the most relevant documents. The self-learning framework progressively refines both pseudo-document generation and retrieval, utilizing unlabeled medical corpora without requiring any relevance-labeled data. Additionally, we present the Chinese Medical Information Retrieval Benchmark (CMIRB), a comprehensive evaluation framework grounded in real-world medical scenarios, encompassing five tasks and ten datasets. By benchmarking ten models on CMIRB, we establish a rigorous standard for evaluating medical information retrieval systems. Experimental results demonstrate that SL-HyDE significantly surpasses existing methods in retrieval accuracy while showcasing strong generalization and scalability across various LLM and retriever configurations. CMIRB data and evaluation code are publicly available at: https://github.com/CMIRB-benchmark/CMIRB.

  • 4 authors
·
Oct 25, 2024 2

How Does Generative Retrieval Scale to Millions of Passages?

Popularized by the Differentiable Search Index, the emerging paradigm of generative retrieval re-frames the classic information retrieval problem into a sequence-to-sequence modeling task, forgoing external indices and encoding an entire document corpus within a single Transformer. Although many different approaches have been proposed to improve the effectiveness of generative retrieval, they have only been evaluated on document corpora on the order of 100k in size. We conduct the first empirical study of generative retrieval techniques across various corpus scales, ultimately scaling up to the entire MS MARCO passage ranking task with a corpus of 8.8M passages and evaluating model sizes up to 11B parameters. We uncover several findings about scaling generative retrieval to millions of passages; notably, the central importance of using synthetic queries as document representations during indexing, the ineffectiveness of existing proposed architecture modifications when accounting for compute cost, and the limits of naively scaling model parameters with respect to retrieval performance. While we find that generative retrieval is competitive with state-of-the-art dual encoders on small corpora, scaling to millions of passages remains an important and unsolved challenge. We believe these findings will be valuable for the community to clarify the current state of generative retrieval, highlight the unique challenges, and inspire new research directions.

  • 8 authors
·
May 19, 2023

Can LLMs Be Trusted for Evaluating RAG Systems? A Survey of Methods and Datasets

Retrieval-Augmented Generation (RAG) has advanced significantly in recent years. The complexity of RAG systems, which involve multiple components-such as indexing, retrieval, and generation-along with numerous other parameters, poses substantial challenges for systematic evaluation and quality enhancement. Previous research highlights that evaluating RAG systems is essential for documenting advancements, comparing configurations, and identifying effective approaches for domain-specific applications. This study systematically reviews 63 academic articles to provide a comprehensive overview of state-of-the-art RAG evaluation methodologies, focusing on four key areas: datasets, retrievers, indexing and databases, and the generator component. We observe the feasibility of an automated evaluation approach for each component of a RAG system, leveraging an LLM capable of both generating evaluation datasets and conducting evaluations. In addition, we found that further practical research is essential to provide companies with clear guidance on the do's and don'ts of implementing and evaluating RAG systems. By synthesizing evaluation approaches for key RAG components and emphasizing the creation and adaptation of domain-specific datasets for benchmarking, we contribute to the advancement of systematic evaluation methods and the improvement of evaluation rigor for RAG systems. Furthermore, by examining the interplay between automated approaches leveraging LLMs and human judgment, we contribute to the ongoing discourse on balancing automation and human input, clarifying their respective contributions, limitations, and challenges in achieving robust and reliable evaluations.

  • 3 authors
·
Apr 28

MetaGen Blended RAG: Higher Accuracy for Domain-Specific Q&A Without Fine-Tuning

Despite the widespread exploration of Retrieval-Augmented Generation (RAG), its deployment in enterprises for domain-specific datasets remains limited due to poor answer accuracy. These corpora, often shielded behind firewalls in private enterprise knowledge bases, having complex, domain-specific terminology, rarely seen by LLMs during pre-training; exhibit significant semantic variability across domains (like networking, military, or legal, etc.), or even within a single domain like medicine, and thus result in poor context precision for RAG systems. Currently, in such situations, fine-tuning or RAG with fine-tuning is attempted, but these approaches are slow, expensive, and lack generalization for accuracy as the new domain-specific data emerges. We propose an approach for Enterprise Search that focuses on enhancing the retriever for a domain-specific corpus through hybrid query indexes and metadata enrichment. This 'MetaGen Blended RAG' method constructs a metadata generation pipeline using key concepts, topics, and acronyms, and then creates a metadata-enriched hybrid index with boosted search queries. This approach avoids overfitting and generalizes effectively across domains. On the PubMedQA benchmark for the biomedical domain, the proposed method achieves 82% retrieval accuracy and 77% RAG accuracy, surpassing all previous RAG accuracy results without fine-tuning and sets a new benchmark for zero-shot results while outperforming much larger models like GPT3.5. The results are even comparable to the best fine-tuned models on this dataset, and we further demonstrate the robustness and scalability of the approach by evaluating it on other Q&A datasets like SQuAD, NQ etc.

  • 3 authors
·
May 23

CliniQ: A Multi-faceted Benchmark for Electronic Health Record Retrieval with Semantic Match Assessment

Electronic Health Record (EHR) retrieval plays a pivotal role in various clinical tasks, but its development has been severely impeded by the lack of publicly available benchmarks. In this paper, we introduce a novel public EHR retrieval benchmark, CliniQ, to address this gap. We consider two retrieval settings: Single-Patient Retrieval and Multi-Patient Retrieval, reflecting various real-world scenarios. Single-Patient Retrieval focuses on finding relevant parts within a patient note, while Multi-Patient Retrieval involves retrieving EHRs from multiple patients. We build our benchmark upon 1,000 discharge summary notes along with the ICD codes and prescription labels from MIMIC-III, and collect 1,246 unique queries with 77,206 relevance judgments by further leveraging powerful LLMs as annotators. Additionally, we include a novel assessment of the semantic gap issue in EHR retrieval by categorizing matching types into string match and four types of semantic matches. On our proposed benchmark, we conduct a comprehensive evaluation of various retrieval methods, ranging from conventional exact match to popular dense retrievers. Our experiments find that BM25 sets a strong baseline and performs competitively to the dense retrievers, and general domain dense retrievers surprisingly outperform those designed for the medical domain. In-depth analyses on various matching types reveal the strengths and drawbacks of different methods, enlightening the potential for targeted improvement. We believe that our benchmark will stimulate the research communities to advance EHR retrieval systems.

  • 8 authors
·
Feb 10

CRUD-RAG: A Comprehensive Chinese Benchmark for Retrieval-Augmented Generation of Large Language Models

Retrieval-Augmented Generation (RAG) is a technique that enhances the capabilities of large language models (LLMs) by incorporating external knowledge sources. This method addresses common LLM limitations, including outdated information and the tendency to produce inaccurate "hallucinated" content. However, the evaluation of RAG systems is challenging, as existing benchmarks are limited in scope and diversity. Most of the current benchmarks predominantly assess question-answering applications, overlooking the broader spectrum of situations where RAG could prove advantageous. Moreover, they only evaluate the performance of the LLM component of the RAG pipeline in the experiments, and neglect the influence of the retrieval component and the external knowledge database. To address these issues, this paper constructs a large-scale and more comprehensive benchmark, and evaluates all the components of RAG systems in various RAG application scenarios. Specifically, we have categorized the range of RAG applications into four distinct types-Create, Read, Update, and Delete (CRUD), each representing a unique use case. "Create" refers to scenarios requiring the generation of original, varied content. "Read" involves responding to intricate questions in knowledge-intensive situations. "Update" focuses on revising and rectifying inaccuracies or inconsistencies in pre-existing texts. "Delete" pertains to the task of summarizing extensive texts into more concise forms. For each of these CRUD categories, we have developed comprehensive datasets to evaluate the performance of RAG systems. We also analyze the effects of various components of the RAG system, such as the retriever, the context length, the knowledge base construction, and the LLM. Finally, we provide useful insights for optimizing the RAG technology for different scenarios.

  • 10 authors
·
Jan 30, 2024

Enhancing Health Information Retrieval with RAG by Prioritizing Topical Relevance and Factual Accuracy

The exponential surge in online health information, coupled with its increasing use by non-experts, highlights the pressing need for advanced Health Information Retrieval models that consider not only topical relevance but also the factual accuracy of the retrieved information, given the potential risks associated with health misinformation. To this aim, this paper introduces a solution driven by Retrieval-Augmented Generation (RAG), which leverages the capabilities of generative Large Language Models (LLMs) to enhance the retrieval of health-related documents grounded in scientific evidence. In particular, we propose a three-stage model: in the first stage, the user's query is employed to retrieve topically relevant passages with associated references from a knowledge base constituted by scientific literature. In the second stage, these passages, alongside the initial query, are processed by LLMs to generate a contextually relevant rich text (GenText). In the last stage, the documents to be retrieved are evaluated and ranked both from the point of view of topical relevance and factual accuracy by means of their comparison with GenText, either through stance detection or semantic similarity. In addition to calculating factual accuracy, GenText can offer a layer of explainability for it, aiding users in understanding the reasoning behind the retrieval. Experimental evaluation of our model on benchmark datasets and against baseline models demonstrates its effectiveness in enhancing the retrieval of both topically relevant and factually accurate health information, thus presenting a significant step forward in the health misinformation mitigation problem.

  • 2 authors
·
Feb 7

Enhancing Retrieval-Augmented Large Language Models with Iterative Retrieval-Generation Synergy

Large language models are powerful text processors and reasoners, but are still subject to limitations including outdated knowledge and hallucinations, which necessitates connecting them to the world. Retrieval-augmented large language models have raised extensive attention for grounding model generation on external knowledge. However, retrievers struggle to capture relevance, especially for queries with complex information needs. Recent work has proposed to improve relevance modeling by having large language models actively involved in retrieval, i.e., to improve retrieval with generation. In this paper, we show that strong performance can be achieved by a method we call Iter-RetGen, which synergizes retrieval and generation in an iterative manner. A model output shows what might be needed to finish a task, and thus provides an informative context for retrieving more relevant knowledge which in turn helps generate a better output in the next iteration. Compared with recent work which interleaves retrieval with generation when producing an output, Iter-RetGen processes all retrieved knowledge as a whole and largely preserves the flexibility in generation without structural constraints. We evaluate Iter-RetGen on multi-hop question answering, fact verification, and commonsense reasoning, and show that it can flexibly leverage parametric knowledge and non-parametric knowledge, and is superior to or competitive with state-of-the-art retrieval-augmented baselines while causing fewer overheads of retrieval and generation. We can further improve performance via generation-augmented retrieval adaptation.

  • 6 authors
·
May 24, 2023

MSRS: Evaluating Multi-Source Retrieval-Augmented Generation

Retrieval-augmented systems are typically evaluated in settings where information required to answer the query can be found within a single source or the answer is short-form or factoid-based. However, many real-world applications demand the ability to integrate and summarize information scattered across multiple sources, where no single source is sufficient to respond to the user's question. In such settings, the retrieval component of a RAG pipeline must recognize a variety of relevance signals, and the generation component must connect and synthesize information across multiple sources. We present a scalable framework for constructing evaluation benchmarks that challenge RAG systems to integrate information across distinct sources and generate long-form responses. Using our framework, we build two new benchmarks on Multi-Source Retrieval and Synthesis: MSRS-Story and MSRS-Meet, representing narrative synthesis and summarization tasks, respectively, that require retrieval from large collections. Our extensive experiments with various RAG pipelines -- including sparse and dense retrievers combined with frontier LLMs -- reveal that generation quality is highly dependent on retrieval effectiveness, which varies greatly by task. While multi-source synthesis proves challenging even in an oracle retrieval setting, we find that reasoning models significantly outperform standard LLMs at this distinct step.

  • 7 authors
·
Aug 28

ARK: Answer-Centric Retriever Tuning via KG-augmented Curriculum Learning

Retrieval-Augmented Generation (RAG) has emerged as a powerful framework for knowledge-intensive tasks, yet its effectiveness in long-context scenarios is often bottlenecked by the retriever's inability to distinguish sparse yet crucial evidence. Standard retrievers, optimized for query-document similarity, frequently fail to align with the downstream goal of generating a precise answer. To bridge this gap, we propose a novel fine-tuning framework that optimizes the retriever for Answer Alignment. Specifically, we first identify high-quality positive chunks by evaluating their sufficiency to generate the correct answer. We then employ a curriculum-based contrastive learning scheme to fine-tune the retriever. This curriculum leverages LLM-constructed Knowledge Graphs (KGs) to generate augmented queries, which in turn mine progressively challenging hard negatives. This process trains the retriever to distinguish the answer-sufficient positive chunks from these nuanced distractors, enhancing its generalization. Extensive experiments on 10 datasets from the Ultradomain and LongBench benchmarks demonstrate that our fine-tuned retriever achieves state-of-the-art performance, improving 14.5% over the base model without substantial architectural modifications and maintaining strong efficiency for long-context RAG. Our work presents a robust and effective methodology for building truly answer-centric retrievers.

  • 3 authors
·
Nov 20

Worse than Zero-shot? A Fact-Checking Dataset for Evaluating the Robustness of RAG Against Misleading Retrievals

Retrieval-augmented generation (RAG) has shown impressive capabilities in mitigating hallucinations in large language models (LLMs). However, LLMs struggle to handle misleading retrievals and often fail to maintain their own reasoning when exposed to conflicting or selectively-framed evidence, making them vulnerable to real-world misinformation. In such real-world retrieval scenarios, misleading and conflicting information is rampant, particularly in the political domain, where evidence is often selectively framed, incomplete, or polarized. However, existing RAG benchmarks largely assume a clean retrieval setting, where models succeed by accurately retrieving and generating answers from gold-standard documents. This assumption fails to align with real-world conditions, leading to an overestimation of RAG system performance. To bridge this gap, we introduce RAGuard, a fact-checking dataset designed to evaluate the robustness of RAG systems against misleading retrievals. Unlike prior benchmarks that rely on synthetic noise, our dataset constructs its retrieval corpus from Reddit discussions, capturing naturally occurring misinformation. It categorizes retrieved evidence into three types: supporting, misleading, and irrelevant, providing a realistic and challenging testbed for assessing how well RAG systems navigate different retrieval information. Our benchmark experiments reveal that when exposed to misleading retrievals, all tested LLM-powered RAG systems perform worse than their zero-shot baselines (i.e., no retrieval at all), highlighting their susceptibility to noisy environments. To the best of our knowledge, RAGuard is the first benchmark to systematically assess RAG robustness against misleading evidence. We expect this benchmark will drive future research toward improving RAG systems beyond idealized datasets, making them more reliable for real-world applications.

  • 5 authors
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Feb 22

Are Large Language Models Good at Utility Judgments?

Retrieval-augmented generation (RAG) is considered to be a promising approach to alleviate the hallucination issue of large language models (LLMs), and it has received widespread attention from researchers recently. Due to the limitation in the semantic understanding of retrieval models, the success of RAG heavily lies on the ability of LLMs to identify passages with utility. Recent efforts have explored the ability of LLMs to assess the relevance of passages in retrieval, but there has been limited work on evaluating the utility of passages in supporting question answering. In this work, we conduct a comprehensive study about the capabilities of LLMs in utility evaluation for open-domain QA. Specifically, we introduce a benchmarking procedure and collection of candidate passages with different characteristics, facilitating a series of experiments with five representative LLMs. Our experiments reveal that: (i) well-instructed LLMs can distinguish between relevance and utility, and that LLMs are highly receptive to newly generated counterfactual passages. Moreover, (ii) we scrutinize key factors that affect utility judgments in the instruction design. And finally, (iii) to verify the efficacy of utility judgments in practical retrieval augmentation applications, we delve into LLMs' QA capabilities using the evidence judged with utility and direct dense retrieval results. (iv) We propose a k-sampling, listwise approach to reduce the dependency of LLMs on the sequence of input passages, thereby facilitating subsequent answer generation. We believe that the way we formalize and study the problem along with our findings contributes to a critical assessment of retrieval-augmented LLMs. Our code and benchmark can be found at https://github.com/ict-bigdatalab/utility_judgments.

  • 6 authors
·
Mar 28, 2024

Benchmarking Large Language Models in Retrieval-Augmented Generation

Retrieval-Augmented Generation (RAG) is a promising approach for mitigating the hallucination of large language models (LLMs). However, existing research lacks rigorous evaluation of the impact of retrieval-augmented generation on different large language models, which make it challenging to identify the potential bottlenecks in the capabilities of RAG for different LLMs. In this paper, we systematically investigate the impact of Retrieval-Augmented Generation on large language models. We analyze the performance of different large language models in 4 fundamental abilities required for RAG, including noise robustness, negative rejection, information integration, and counterfactual robustness. To this end, we establish Retrieval-Augmented Generation Benchmark (RGB), a new corpus for RAG evaluation in both English and Chinese. RGB divides the instances within the benchmark into 4 separate testbeds based on the aforementioned fundamental abilities required to resolve the case. Then we evaluate 6 representative LLMs on RGB to diagnose the challenges of current LLMs when applying RAG. Evaluation reveals that while LLMs exhibit a certain degree of noise robustness, they still struggle significantly in terms of negative rejection, information integration, and dealing with false information. The aforementioned assessment outcomes indicate that there is still a considerable journey ahead to effectively apply RAG to LLMs.

  • 4 authors
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Sep 4, 2023

A Survey on Knowledge-Oriented Retrieval-Augmented Generation

Retrieval-Augmented Generation (RAG) has gained significant attention in recent years for its potential to enhance natural language understanding and generation by combining large-scale retrieval systems with generative models. RAG leverages external knowledge sources, such as documents, databases, or structured data, to improve model performance and generate more accurate and contextually relevant outputs. This survey aims to provide a comprehensive overview of RAG by examining its fundamental components, including retrieval mechanisms, generation processes, and the integration between the two. We discuss the key characteristics of RAG, such as its ability to augment generative models with dynamic external knowledge, and the challenges associated with aligning retrieved information with generative objectives. We also present a taxonomy that categorizes RAG methods, ranging from basic retrieval-augmented approaches to more advanced models incorporating multi-modal data and reasoning capabilities. Additionally, we review the evaluation benchmarks and datasets commonly used to assess RAG systems, along with a detailed exploration of its applications in fields such as question answering, summarization, and information retrieval. Finally, we highlight emerging research directions and opportunities for improving RAG systems, such as enhanced retrieval efficiency, model interpretability, and domain-specific adaptations. This paper concludes by outlining the prospects for RAG in addressing real-world challenges and its potential to drive further advancements in natural language processing.

  • 12 authors
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Mar 10

Long-Context LLMs Meet RAG: Overcoming Challenges for Long Inputs in RAG

Retrieval-augmented generation (RAG) empowers large language models (LLMs) to utilize external knowledge sources. The increasing capacity of LLMs to process longer input sequences opens up avenues for providing more retrieved information, to potentially enhance the quality of generated outputs. It is plausible to assume that a larger retrieval set would contain more relevant information (higher recall), that might result in improved performance. However, our empirical findings demonstrate that for many long-context LLMs, the quality of generated output initially improves first, but then subsequently declines as the number of retrieved passages increases. This paper investigates this phenomenon, identifying the detrimental impact of retrieved "hard negatives" as a key contributor. To mitigate this and enhance the robustness of long-context LLM-based RAG, we propose both training-free and training-based approaches. We first showcase the effectiveness of retrieval reordering as a simple yet powerful training-free optimization. Furthermore, we explore training-based methods, specifically RAG-specific implicit LLM fine-tuning and RAG-oriented fine-tuning with intermediate reasoning, demonstrating their capacity for substantial performance gains. Finally, we conduct a systematic analysis of design choices for these training-based methods, including data distribution, retriever selection, and training context length.

  • 4 authors
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Oct 8, 2024

Retrieval Augmented Generation Evaluation for Health Documents

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the most relevant information at a given moment. Retrieval Augmented Generation (RAG) is a promising method to leverage the potential of LLMs while enhancing the accuracy of their outcomes. This report assesses the potentials and shortcomings of such approaches in the automatic knowledge synthesis of different types of documents in the health domain. To this end, it describes: (1) an internally developed proof of concept pipeline that employs state-of-the-art practices to deliver safe and trustable analysis for healthcare documents and scientific papers called RAGEv (Retrieval Augmented Generation Evaluation); (2) a set of evaluation tools for LLM-based document retrieval and generation; (3) a benchmark dataset to verify the accuracy and veracity of the results called RAGEv-Bench. It concludes that careful implementations of RAG techniques could minimize most of the common problems in the use of LLMs for document processing in the health domain, obtaining very high scores both on short yes/no answers and long answers. There is a high potential for incorporating it into the day-to-day work of policy support tasks, but additional efforts are required to obtain a consistent and trustworthy tool.

  • 11 authors
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May 7

Improving Medical Reasoning through Retrieval and Self-Reflection with Retrieval-Augmented Large Language Models

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that still cannot be handled with the encoded knowledge of LLMs, various retrieval-augmented generation (RAG) methods have been developed by searching documents from the knowledge corpus and appending them unconditionally or selectively to the input of LLMs for generation. However, when applying existing methods to different domain-specific problems, poor generalization becomes apparent, leading to fetching incorrect documents or making inaccurate judgments. In this paper, we introduce Self-BioRAG, a framework reliable for biomedical text that specializes in generating explanations, retrieving domain-specific documents, and self-reflecting generated responses. We utilize 84k filtered biomedical instruction sets to train Self-BioRAG that can assess its generated explanations with customized reflective tokens. Our work proves that domain-specific components, such as a retriever, domain-related document corpus, and instruction sets are necessary for adhering to domain-related instructions. Using three major medical question-answering benchmark datasets, experimental results of Self-BioRAG demonstrate significant performance gains by achieving a 7.2% absolute improvement on average over the state-of-the-art open-foundation model with a parameter size of 7B or less. Overall, we analyze that Self-BioRAG finds the clues in the question, retrieves relevant documents if needed, and understands how to answer with information from retrieved documents and encoded knowledge as a medical expert does. We release our data and code for training our framework components and model weights (7B and 13B) to enhance capabilities in biomedical and clinical domains.

  • 4 authors
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Jan 26, 2024

Scaling Test-Time Inference with Policy-Optimized, Dynamic Retrieval-Augmented Generation via KV Caching and Decoding

We present a comprehensive framework for enhancing Retrieval-Augmented Generation (RAG) systems through dynamic retrieval strategies and reinforcement fine-tuning. This approach significantly improves large language models on knowledge-intensive tasks, including opendomain question answering and complex reasoning. Our framework integrates two complementary techniques: Policy-Optimized RetrievalAugmented Generation (PORAG), which optimizes the use of retrieved information, and Adaptive Token-Layer Attention Scoring (ATLAS), which dynamically determines retrieval timing and content based on contextual needs. Together, these techniques enhance both the utilization and relevance of retrieved content, improving factual accuracy and response quality. Designed as a lightweight solution compatible with any Transformer-based LLM without requiring additional training, our framework excels in knowledge-intensive tasks, boosting output accuracy in RAG settings. We further propose CRITIC, a novel method to selectively compress key-value caches by token importance, mitigating memory bottlenecks in long-context applications. The framework also incorporates test-time scaling techniques to dynamically balance reasoning depth and computational resources, alongside optimized decoding strategies for faster inference. Experiments on benchmark datasets show that our framework reduces hallucinations, strengthens domain-specific reasoning, and achieves significant efficiency and scalability gains over traditional RAG systems. This integrated approach advances the development of robust, efficient, and scalable RAG systems across diverse applications.

  • 2 authors
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Apr 1

Zero-Indexing Internet Search Augmented Generation for Large Language Models

Retrieval augmented generation has emerged as an effective method to enhance large language model performance. This approach typically relies on an internal retrieval module that uses various indexing mechanisms to manage a static pre-processed corpus. However, such a paradigm often falls short when it is necessary to integrate the most up-to-date information that has not been updated into the corpus during generative inference time. In this paper, we explore an alternative approach that leverages standard search engine APIs to dynamically integrate the latest online information (without maintaining any index for any fixed corpus), thereby improving the quality of generated content. We design a collaborative LLM-based paradigm, where we include: (i) a parser-LLM that determines if the Internet augmented generation is demanded and extracts the search keywords if so with a single inference; (ii) a mixed ranking strategy that re-ranks the retrieved HTML files to eliminate bias introduced from the search engine API; and (iii) an extractor-LLM that can accurately and efficiently extract relevant information from the fresh content in each HTML file. We conduct extensive empirical studies to evaluate the performance of this Internet search augmented generation paradigm. The experimental results demonstrate that our method generates content with significantly improved quality. Our system has been successfully deployed in a production environment to serve 01.AI's generative inference requests.

  • 8 authors
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Nov 29, 2024

BRIGHT: A Realistic and Challenging Benchmark for Reasoning-Intensive Retrieval

Existing retrieval benchmarks primarily consist of information-seeking queries (e.g., aggregated questions from search engines) where keyword or semantic-based retrieval is usually sufficient. However, many complex real-world queries require in-depth reasoning to identify relevant documents that go beyond surface form matching. For example, finding documentation for a coding question requires understanding the logic and syntax of the functions involved. To better benchmark retrieval on such challenging queries, we introduce BRIGHT, the first text retrieval benchmark that requires intensive reasoning to retrieve relevant documents. BRIGHT is constructed from the 1,398 real-world queries collected from diverse domains (such as economics, psychology, robotics, software engineering, earth sciences, etc.), sourced from naturally occurring or carefully curated human data. Extensive evaluation reveals that even state-of-the-art retrieval models perform poorly on BRIGHT. The leading model on the MTEB leaderboard [38 ], which achieves a score of 59.0 nDCG@10,2 produces a score of nDCG@10 of 18.0 on BRIGHT. We further demonstrate that augmenting queries with Chain-of-Thought reasoning generated by large language models (LLMs) improves performance by up to 12.2 points. Moreover, BRIGHT is robust against data leakage during pretraining of the benchmarked models as we validate by showing similar performance even when documents from the benchmark are included in the training data. We believe that BRIGHT paves the way for future research on retrieval systems in more realistic and challenging settings. Our code and data are available at https://brightbenchmark.github.io.

  • 15 authors
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Jul 16, 2024 2

MRAMG-Bench: A BeyondText Benchmark for Multimodal Retrieval-Augmented Multimodal Generation

Recent advancements in Retrieval-Augmented Generation (RAG) have shown remarkable performance in enhancing response accuracy and relevance by integrating external knowledge into generative models. However, existing RAG methods primarily focus on providing text-only answers, even in multimodal retrieval-augmented generation scenarios. In this work, we introduce the Multimodal Retrieval-Augmented Multimodal Generation (MRAMG) task, which aims to generate answers that combine both text and images, fully leveraging the multimodal data within a corpus. Despite the importance of this task, there is a notable absence of a comprehensive benchmark to effectively evaluate MRAMG performance. To bridge this gap, we introduce the MRAMG-Bench, a carefully curated, human-annotated dataset comprising 4,346 documents, 14,190 images, and 4,800 QA pairs, sourced from three categories: Web Data, Academic Papers, and Lifestyle. The dataset incorporates diverse difficulty levels and complex multi-image scenarios, providing a robust foundation for evaluating multimodal generation tasks. To facilitate rigorous evaluation, our MRAMG-Bench incorporates a comprehensive suite of both statistical and LLM-based metrics, enabling a thorough analysis of the performance of popular generative models in the MRAMG task. Besides, we propose an efficient multimodal answer generation framework that leverages both LLMs and MLLMs to generate multimodal responses. Our datasets are available at: https://huggingface.co/MRAMG.

  • 6 authors
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Feb 6

From Retrieval to Generation: Comparing Different Approaches

Knowledge-intensive tasks, particularly open-domain question answering (ODQA), document reranking, and retrieval-augmented language modeling, require a balance between retrieval accuracy and generative flexibility. Traditional retrieval models such as BM25 and Dense Passage Retrieval (DPR), efficiently retrieve from large corpora but often lack semantic depth. Generative models like GPT-4-o provide richer contextual understanding but face challenges in maintaining factual consistency. In this work, we conduct a systematic evaluation of retrieval-based, generation-based, and hybrid models, with a primary focus on their performance in ODQA and related retrieval-augmented tasks. Our results show that dense retrievers, particularly DPR, achieve strong performance in ODQA with a top-1 accuracy of 50.17\% on NQ, while hybrid models improve nDCG@10 scores on BEIR from 43.42 (BM25) to 52.59, demonstrating their strength in document reranking. Additionally, we analyze language modeling tasks using WikiText-103, showing that retrieval-based approaches like BM25 achieve lower perplexity compared to generative and hybrid methods, highlighting their utility in retrieval-augmented generation. By providing detailed comparisons and practical insights into the conditions where each approach excels, we aim to facilitate future optimizations in retrieval, reranking, and generative models for ODQA and related knowledge-intensive applications.

  • 5 authors
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Feb 27

HANRAG: Heuristic Accurate Noise-resistant Retrieval-Augmented Generation for Multi-hop Question Answering

The Retrieval-Augmented Generation (RAG) approach enhances question-answering systems and dialogue generation tasks by integrating information retrieval (IR) technologies with large language models (LLMs). This strategy, which retrieves information from external knowledge bases to bolster the response capabilities of generative models, has achieved certain successes. However, current RAG methods still face numerous challenges when dealing with multi-hop queries. For instance, some approaches overly rely on iterative retrieval, wasting too many retrieval steps on compound queries. Additionally, using the original complex query for retrieval may fail to capture content relevant to specific sub-queries, resulting in noisy retrieved content. If the noise is not managed, it can lead to the problem of noise accumulation. To address these issues, we introduce HANRAG, a novel heuristic-based framework designed to efficiently tackle problems of varying complexity. Driven by a powerful revelator, HANRAG routes queries, decomposes them into sub-queries, and filters noise from retrieved documents. This enhances the system's adaptability and noise resistance, making it highly capable of handling diverse queries. We compare the proposed framework against other leading industry methods across various benchmarks. The results demonstrate that our framework obtains superior performance in both single-hop and multi-hop question-answering tasks.

xRAG: Extreme Context Compression for Retrieval-augmented Generation with One Token

This paper introduces xRAG, an innovative context compression method tailored for retrieval-augmented generation. xRAG reinterprets document embeddings in dense retrieval--traditionally used solely for retrieval--as features from the retrieval modality. By employing a modality fusion methodology, xRAG seamlessly integrates these embeddings into the language model representation space, effectively eliminating the need for their textual counterparts and achieving an extreme compression rate. In xRAG, the only trainable component is the modality bridge, while both the retriever and the language model remain frozen. This design choice allows for the reuse of offline-constructed document embeddings and preserves the plug-and-play nature of retrieval augmentation. Experimental results demonstrate that xRAG achieves an average improvement of over 10% across six knowledge-intensive tasks, adaptable to various language model backbones, ranging from a dense 7B model to an 8x7B Mixture of Experts configuration. xRAG not only significantly outperforms previous context compression methods but also matches the performance of uncompressed models on several datasets, while reducing overall FLOPs by a factor of 3.53. Our work pioneers new directions in retrieval-augmented generation from the perspective of multimodality fusion, and we hope it lays the foundation for future efficient and scalable retrieval-augmented systems

  • 8 authors
·
May 22, 2024

TemMed-Bench: Evaluating Temporal Medical Image Reasoning in Vision-Language Models

Existing medical reasoning benchmarks for vision-language models primarily focus on analyzing a patient's condition based on an image from a single visit. However, this setting deviates significantly from real-world clinical practice, where doctors typically refer to a patient's historical conditions to provide a comprehensive assessment by tracking their changes over time. In this paper, we introduce TemMed-Bench, the first benchmark designed for analyzing changes in patients' conditions between different clinical visits, which challenges large vision-language models (LVLMs) to reason over temporal medical images. TemMed-Bench consists of a test set comprising three tasks - visual question-answering (VQA), report generation, and image-pair selection - and a supplementary knowledge corpus of over 17,000 instances. With TemMed-Bench, we conduct an evaluation of six proprietary and six open-source LVLMs. Our results show that most LVLMs lack the ability to analyze patients' condition changes over temporal medical images, and a large proportion perform only at a random-guessing level in the closed-book setting. In contrast, GPT o3, o4-mini and Claude 3.5 Sonnet demonstrate comparatively decent performance, though they have yet to reach the desired level. Furthermore, we explore augmenting the input with both retrieved visual and textual modalities in the medical domain. We also show that multi-modal retrieval augmentation yields notably higher performance gains than no retrieval and textual retrieval alone across most models on our benchmark, with the VQA task showing an average improvement of 2.59%. Overall, we compose a benchmark grounded on real-world clinical practice, and it reveals LVLMs' limitations in temporal medical image reasoning, as well as highlighting the use of multi-modal retrieval augmentation as a potentially promising direction worth exploring to address this challenge.

  • 6 authors
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Sep 29

JMLR: Joint Medical LLM and Retrieval Training for Enhancing Reasoning and Professional Question Answering Capability

Large Language Models (LLMs) have demonstrated a remarkable potential in medical knowledge acquisition and question-answering. However, LLMs can potentially hallucinate and yield factually incorrect outcomes, even with domain-specific pretraining. Previously, retrieval augmented generation (RAG) has limited success in addressing hallucinations. Unlike previous methods in RAG where the retrieval model was trained separately from the LLM, we introduce JMLR (for Jointly trains LLM and information Retrieval) during the fine-tuning phase. The synchronized training mechanism enhances JMLR's ability to retrieve clinical guidelines and leverage medical knowledge to reason and answer questions and reduces the demand for computational resources. We evaluated JMLR on the important medical question-answering application. Our experimental results demonstrate that JMLR-13B (70.5%) outperforms a previous state-of-the-art open-source model using conventional pre-training and fine-tuning Meditron-70B (68.9%) and Llama2-13B with RAG (67.7%) on a medical question-answering dataset. Comprehensive evaluations reveal JMLR-13B enhances reasoning quality and reduces hallucinations better than Claude3-Opus. Additionally, JMLR-13B (148 GPU hours) also trains much faster than Meditron-70B (42630 GPU hours). Through this work, we provide a new and efficient knowledge enhancement method for healthcare, demonstrating the potential of integrating retrieval and LLM training for medical question-answering systems.

  • 4 authors
·
Feb 27, 2024

Benchmarking Information Retrieval Models on Complex Retrieval Tasks

Large language models (LLMs) are incredible and versatile tools for text-based tasks that have enabled countless, previously unimaginable, applications. Retrieval models, in contrast, have not yet seen such capable general-purpose models emerge. To achieve this goal, retrieval models must be able to perform complex retrieval tasks, where queries contain multiple parts, constraints, or requirements in natural language. These tasks represent a natural progression from the simple, single-aspect queries that are used in the vast majority of existing, commonly used evaluation sets. Complex queries naturally arise as people expect search systems to handle more specific and often ambitious information requests, as is demonstrated by how people use LLM-based information systems. Despite the growing desire for retrieval models to expand their capabilities in complex retrieval tasks, there exist limited resources to assess the ability of retrieval models on a comprehensive set of diverse complex tasks. The few resources that do exist feature a limited scope and often lack realistic settings making it hard to know the true capabilities of retrieval models on complex real-world retrieval tasks. To address this shortcoming and spur innovation in next-generation retrieval models, we construct a diverse and realistic set of complex retrieval tasks and benchmark a representative set of state-of-the-art retrieval models. Additionally, we explore the impact of LLM-based query expansion and rewriting on retrieval quality. Our results show that even the best models struggle to produce high-quality retrieval results with the highest average nDCG@10 of only 0.346 and R@100 of only 0.587 across all tasks. Although LLM augmentation can help weaker models, the strongest model has decreased performance across all metrics with all rewriting techniques.

  • 2 authors
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Sep 8 2

Are We on the Right Way for Assessing Document Retrieval-Augmented Generation?

Retrieval-Augmented Generation (RAG) systems using Multimodal Large Language Models (MLLMs) show great promise for complex document understanding, yet their development is critically hampered by inadequate evaluation. Current benchmarks often focus on specific part of document RAG system and use synthetic data with incomplete ground truth and evidence labels, therefore failing to reflect real-world bottlenecks and challenges. To overcome these limitations, we introduce Double-Bench: a new large-scale, multilingual, and multimodal evaluation system that is able to produce fine-grained assessment to each component within document RAG systems. It comprises 3,276 documents (72,880 pages) and 5,168 single- and multi-hop queries across 6 languages and 4 document types with streamlined dynamic update support for potential data contamination issues. Queries are grounded in exhaustively scanned evidence pages and verified by human experts to ensure maximum quality and completeness. Our comprehensive experiments across 9 state-of-the-art embedding models, 4 MLLMs and 4 end-to-end document RAG frameworks demonstrate the gap between text and visual embedding models is narrowing, highlighting the need in building stronger document retrieval models. Our findings also reveal the over-confidence dilemma within current document RAG frameworks that tend to provide answer even without evidence support. We hope our fully open-source Double-Bench provide a rigorous foundation for future research in advanced document RAG systems. We plan to retrieve timely corpus and release new benchmarks on an annual basis.

MemoRAG: Moving towards Next-Gen RAG Via Memory-Inspired Knowledge Discovery

Retrieval-Augmented Generation (RAG) leverages retrieval tools to access external databases, thereby enhancing the generation quality of large language models (LLMs) through optimized context. However, the existing retrieval methods are constrained inherently, as they can only perform relevance matching between explicitly stated queries and well-formed knowledge, but unable to handle tasks involving ambiguous information needs or unstructured knowledge. Consequently, existing RAG systems are primarily effective for straightforward question-answering tasks. In this work, we propose MemoRAG, a novel retrieval-augmented generation paradigm empowered by long-term memory. MemoRAG adopts a dual-system architecture. On the one hand, it employs a light but long-range LLM to form the global memory of database. Once a task is presented, it generates draft answers, cluing the retrieval tools to locate useful information within the database. On the other hand, it leverages an expensive but expressive LLM, which generates the ultimate answer based on the retrieved information. Building on this general framework, we further optimize MemoRAG's performance by enhancing its cluing mechanism and memorization capacity. In our experiment, MemoRAG achieves superior performance across a variety of evaluation tasks, including both complex ones where conventional RAG fails and straightforward ones where RAG is commonly applied.

  • 5 authors
·
Sep 9, 2024 4

InsertRank: LLMs can reason over BM25 scores to Improve Listwise Reranking

Large Language Models (LLMs) have demonstrated significant strides across various information retrieval tasks, particularly as rerankers, owing to their strong generalization and knowledge-transfer capabilities acquired from extensive pretraining. In parallel, the rise of LLM-based chat interfaces has raised user expectations, encouraging users to pose more complex queries that necessitate retrieval by ``reasoning'' over documents rather than through simple keyword matching or semantic similarity. While some recent efforts have exploited reasoning abilities of LLMs for reranking such queries, considerable potential for improvement remains. In that regards, we introduce InsertRank, an LLM-based reranker that leverages lexical signals like BM25 scores during reranking to further improve retrieval performance. InsertRank demonstrates improved retrieval effectiveness on -- BRIGHT, a reasoning benchmark spanning 12 diverse domains, and R2MED, a specialized medical reasoning retrieval benchmark spanning 8 different tasks. We conduct an exhaustive evaluation and several ablation studies and demonstrate that InsertRank consistently improves retrieval effectiveness across multiple families of LLMs, including GPT, Gemini, and Deepseek models. %In addition, we also conduct ablation studies on normalization by varying the scale of the BM25 scores, and positional bias by shuffling the order of the documents. With Deepseek-R1, InsertRank achieves a score of 37.5 on the BRIGHT benchmark. and 51.1 on the R2MED benchmark, surpassing previous methods.

  • 3 authors
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Jun 16

Enhancing Retrieval-Augmented Generation: A Study of Best Practices

Retrieval-Augmented Generation (RAG) systems have recently shown remarkable advancements by integrating retrieval mechanisms into language models, enhancing their ability to produce more accurate and contextually relevant responses. However, the influence of various components and configurations within RAG systems remains underexplored. A comprehensive understanding of these elements is essential for tailoring RAG systems to complex retrieval tasks and ensuring optimal performance across diverse applications. In this paper, we develop several advanced RAG system designs that incorporate query expansion, various novel retrieval strategies, and a novel Contrastive In-Context Learning RAG. Our study systematically investigates key factors, including language model size, prompt design, document chunk size, knowledge base size, retrieval stride, query expansion techniques, Contrastive In-Context Learning knowledge bases, multilingual knowledge bases, and Focus Mode retrieving relevant context at sentence-level. Through extensive experimentation, we provide a detailed analysis of how these factors influence response quality. Our findings offer actionable insights for developing RAG systems, striking a balance between contextual richness and retrieval-generation efficiency, thereby paving the way for more adaptable and high-performing RAG frameworks in diverse real-world scenarios. Our code and implementation details are publicly available.

  • 4 authors
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Jan 13

MRAG-Bench: Vision-Centric Evaluation for Retrieval-Augmented Multimodal Models

Existing multimodal retrieval benchmarks primarily focus on evaluating whether models can retrieve and utilize external textual knowledge for question answering. However, there are scenarios where retrieving visual information is either more beneficial or easier to access than textual data. In this paper, we introduce a multimodal retrieval-augmented generation benchmark, MRAG-Bench, in which we systematically identify and categorize scenarios where visually augmented knowledge is better than textual knowledge, for instance, more images from varying viewpoints. MRAG-Bench consists of 16,130 images and 1,353 human-annotated multiple-choice questions across 9 distinct scenarios. With MRAG-Bench, we conduct an evaluation of 10 open-source and 4 proprietary large vision-language models (LVLMs). Our results show that all LVLMs exhibit greater improvements when augmented with images compared to textual knowledge, confirming that MRAG-Bench is vision-centric. Additionally, we conduct extensive analysis with MRAG-Bench, which offers valuable insights into retrieval-augmented LVLMs. Notably, the top-performing model, GPT-4o, faces challenges in effectively leveraging retrieved knowledge, achieving only a 5.82% improvement with ground-truth information, in contrast to a 33.16% improvement observed in human participants. These findings highlight the importance of MRAG-Bench in encouraging the community to enhance LVLMs' ability to utilize retrieved visual knowledge more effectively.

  • 7 authors
·
Oct 10, 2024

Meta Knowledge for Retrieval Augmented Large Language Models

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However, constructing RAG systems that can effectively synthesize information from large and diverse set of documents remains a significant challenge. We introduce a novel data-centric RAG workflow for LLMs, transforming the traditional retrieve-then-read system into a more advanced prepare-then-rewrite-then-retrieve-then-read framework, to achieve higher domain expert-level understanding of the knowledge base. Our methodology relies on generating metadata and synthetic Questions and Answers (QA) for each document, as well as introducing the new concept of Meta Knowledge Summary (MK Summary) for metadata-based clusters of documents. The proposed innovations enable personalized user-query augmentation and in-depth information retrieval across the knowledge base. Our research makes two significant contributions: using LLMs as evaluators and employing new comparative performance metrics, we demonstrate that (1) using augmented queries with synthetic question matching significantly outperforms traditional RAG pipelines that rely on document chunking (p < 0.01), and (2) meta knowledge-augmented queries additionally significantly improve retrieval precision and recall, as well as the final answers breadth, depth, relevancy, and specificity. Our methodology is cost-effective, costing less than $20 per 2000 research papers using Claude 3 Haiku, and can be adapted with any fine-tuning of either the language or embedding models to further enhance the performance of end-to-end RAG pipelines.

  • 6 authors
·
Aug 16, 2024

Improving Retrieval-Augmented Large Language Models via Data Importance Learning

Retrieval augmentation enables large language models to take advantage of external knowledge, for example on tasks like question answering and data imputation. However, the performance of such retrieval-augmented models is limited by the data quality of their underlying retrieval corpus. In this paper, we propose an algorithm based on multilinear extension for evaluating the data importance of retrieved data points. There are exponentially many terms in the multilinear extension, and one key contribution of this paper is a polynomial time algorithm that computes exactly, given a retrieval-augmented model with an additive utility function and a validation set, the data importance of data points in the retrieval corpus using the multilinear extension of the model's utility function. We further proposed an even more efficient ({\epsilon}, {\delta})-approximation algorithm. Our experimental results illustrate that we can enhance the performance of large language models by only pruning or reweighting the retrieval corpus, without requiring further training. For some tasks, this even allows a small model (e.g., GPT-JT), augmented with a search engine API, to outperform GPT-3.5 (without retrieval augmentation). Moreover, we show that weights based on multilinear extension can be computed efficiently in practice (e.g., in less than ten minutes for a corpus with 100 million elements).

  • 7 authors
·
Jul 6, 2023

The Chronicles of RAG: The Retriever, the Chunk and the Generator

Retrieval Augmented Generation (RAG) has become one of the most popular paradigms for enabling LLMs to access external data, and also as a mechanism for grounding to mitigate against hallucinations. When implementing RAG you can face several challenges like effective integration of retrieval models, efficient representation learning, data diversity, computational efficiency optimization, evaluation, and quality of text generation. Given all these challenges, every day a new technique to improve RAG appears, making it unfeasible to experiment with all combinations for your problem. In this context, this paper presents good practices to implement, optimize, and evaluate RAG for the Brazilian Portuguese language, focusing on the establishment of a simple pipeline for inference and experiments. We explored a diverse set of methods to answer questions about the first Harry Potter book. To generate the answers we used the OpenAI's gpt-4, gpt-4-1106-preview, gpt-3.5-turbo-1106, and Google's Gemini Pro. Focusing on the quality of the retriever, our approach achieved an improvement of MRR@10 by 35.4% compared to the baseline. When optimizing the input size in the application, we observed that it is possible to further enhance it by 2.4%. Finally, we present the complete architecture of the RAG with our recommendations. As result, we moved from a baseline of 57.88% to a maximum relative score of 98.61%.

  • 8 authors
·
Jan 15, 2024

SFR-RAG: Towards Contextually Faithful LLMs

Retrieval Augmented Generation (RAG), a paradigm that integrates external contextual information with large language models (LLMs) to enhance factual accuracy and relevance, has emerged as a pivotal area in generative AI. The LLMs used in RAG applications are required to faithfully and completely comprehend the provided context and users' questions, avoid hallucination, handle unanswerable, counterfactual or otherwise low-quality and irrelevant contexts, perform complex multi-hop reasoning and produce reliable citations. In this paper, we introduce SFR-RAG, a small LLM that is instruction-tuned with an emphasis on context-grounded generation and hallucination minimization. We also present ContextualBench, a new evaluation framework compiling multiple popular and diverse RAG benchmarks, such as HotpotQA and TriviaQA, with consistent RAG settings to ensure reproducibility and consistency in model assessments. Experimental results demonstrate that our SFR-RAG-9B model outperforms leading baselines such as Command-R+ (104B) and GPT-4o, achieving state-of-the-art results in 3 out of 7 benchmarks in ContextualBench with significantly fewer parameters. The model is also shown to be resilient to alteration in the contextual information and behave appropriately when relevant context is removed. Additionally, the SFR-RAG model maintains competitive performance in general instruction-following tasks and function-calling capabilities.

  • 10 authors
·
Sep 15, 2024

MRMR: A Realistic and Expert-Level Multidisciplinary Benchmark for Reasoning-Intensive Multimodal Retrieval

We introduce MRMR, the first expert-level multidisciplinary multimodal retrieval benchmark requiring intensive reasoning. MRMR contains 1,502 queries spanning 23 domains, with positive documents carefully verified by human experts. Compared to prior benchmarks, MRMR introduces three key advancements. First, it challenges retrieval systems across diverse areas of expertise, enabling fine-grained model comparison across domains. Second, queries are reasoning-intensive, with images requiring deeper interpretation such as diagnosing microscopic slides. We further introduce Contradiction Retrieval, a novel task requiring models to identify conflicting concepts. Finally, queries and documents are constructed as image-text interleaved sequences. Unlike earlier benchmarks restricted to single images or unimodal documents, MRMR offers a realistic setting with multi-image queries and mixed-modality corpus documents. We conduct an extensive evaluation of 4 categories of multimodal retrieval systems and 14 frontier models on MRMR. The text embedding model Qwen3-Embedding with LLM-generated image captions achieves the highest performance, highlighting substantial room for improving multimodal retrieval models. Although latest multimodal models such as Ops-MM-Embedding perform competitively on expert-domain queries, they fall short on reasoning-intensive tasks. We believe that MRMR paves the way for advancing multimodal retrieval in more realistic and challenging scenarios.

  • 8 authors
·
Oct 10 2